Peter Pauwels

Nationality: BelgiumMarital Status: Married, two childrenAge:47 yearsPrivate Address: Ex Maison Lepinois, Chez les FavreF74270 Chessenaz, France Tel: +33.4.50.27.91.24E-mail: peter.pauwels@wanadoo.frCore Scientific Competence Profile: Pharmacology Neuropsychiatry:Schizophrenia: ocaperidone, risperidone, recent Pierre Fabre (PF) antipsychotic (preclinical)Depression/anxiety: 5-HT1B receptor inverse agonist (F 14258, Phase I), three recent PF agents (Phase I, II).Neurology:Stroke: flunarizine, lubeluzole (Phase III),Alzheimer's disease: sabeluzole (Phase III), two recent PF agents (preclinical, phase I)Parkinson's disease: idazoxan (Phase II),Migraine: flunarizine, recent PF agent (Phase II).Pain: recent PF agent (Phase II).Cardiovascular diseases:Hypertension: ketanserin, nebivolol,Cardiac ischemia: R 56865, recent PF agent (preclinical),Atherosclerosis: recent PF agent (Phase II)Cancer:Humanized antibodies against either growth factor receptors or their ligands (preclinical),Bispecific antibody approach to growth factor receptors (preclinical),Immunoconjugates between chemotherapeutic agents and growth factor receptor antibodies (preclinical)Professional Experience: From bench to senior management level2002-present:Managing Director of the Centre d’immunologie Pierre Fabre, Saint-Julien en Genevois, France, reporting to the R&D President. Therapeutic area of interest: Cancer-Antibodies.1998-2002:Deputy Director at the Centre de Recherche Pierre Fabre (CRPF), Castres, reporting to the Research Center Director. 1997-2002:Director of the Cellular and Molecular Biology Department at the Centre de Recherche Pierre Fabre (CRPF), Castres, reporting to the Research Center Director. 1994-1997:Head of the Cellular and Molecular Neurobiology Lab. at the CRPF.1992-1994:Head of the Cellular Neurobiology Lab. at the CRPF.1987-1992:Senior Research Scientist at the Biochemical Pharmacology Department, Janssen Research Foundation, Beerse, Belgium.1984-1987:Scientist at the Biochemical Pharmacology Department, Janssen Research Foundation.1979-1984:PhD Student at the International Institute of Cellular and Molecular Pathology, Brussels, Belgium (Prof. Dr. C. de Duve & Prof. Dr. A. Trouet).1979:Scientist at the Oceanographic Division of Belgian Navy, Oostende, Belgium.Educational Highlights: Professor, DoctorProf. Degree:In Neuroscience, Ministry of National Education Research and Technology, Paris, France, 2000.Ph.D. Degree:In Cellular & Molecular Pathology from the University of Ghent (Prof. Dr. W. Fiers) and the International Institute of Cellular and Molecular Pathology, Brussels (Prof. Dr. A. Trouet), Belgium, 1984.M.Sc. Degree:Rijksuniversiteit Ghent, Belgium, 1974-1978.Biology: Biochemical-Physiological specialization.Languages: multilingualDutch (mother tongue), French (fluent), English (fluent), German (notions)Further details on my curriculum vitae, research activities and scientific publications (145) are available on request